OUR PARTNERS AND COLLABORATORS

Medicenna has exclusive worldwide license rights to a broad portfolio of patents covering our Superkine™ and Empowered Cytokine™ platforms from:

  • Stanford University
  • National Institute of Health
  • Hebrew University of Jerusalem

In addition, Medicenna has assembled an impressive team of world class scientists from top tier research institutions and leading global pharmaceutical and biotechnology companies to harness the full potential of our platforms.


PARTNERING OPPORTUNITIES

Medicenna seeks to be a partner-of-choice for collaborators and licensing partners to develop next generation therapies targeting critical unmet medical needs. With MDNA55 clinical data expected this year from our Phase 2 trial and a robust pre-clinical pipeline of validated Superkines with exceptional potential as stand-alone therapeutics or combined as fusion candidate with antibodies, we are excited to discuss numerous potential partnering opportunities.

MULTIPLE “PIPELINE IN A PRODUCT” OPPORTUNITIES

Product Initial Opportunity Stage Unique Differentiated Profile
MDNA55 Recurrent GBM; Metastatic brain tumors; pediatric CNS cancers Clinical Phase 2b Dual-action immunotherapeutic simultaneously targeting IL-4R expressing tumors and tumor microenvironment
MDNA109
(IL2 Super-Agonist)
Solid tumors Pre-Clinical
(Phase 1/2 trial planned in 2019)
Improved potency and selectivity for Teff over Treg compared to NKTR-214 (Nektar)
MDNA209
(IL2 Super-Antagonist)
Autoimmune diseases Pre-Clinical Broad and potent inhibition of IL2R expressing cells compared to DEL106 (Delinia) and Daclizumab (Abbvie/Biogen)
MDNA413
(IL13 Super-Antagonist)
Solid tumors; Th2 diseases Pre-Clinical Unique MOA targeting Type 2 IL4/IL13 receptor compared to Dupilumab (Sanofi) and PRS-060 (Pieris)
MDNA132
(IL13 Superkine)
Solid tumor targeting for CAR-T Pre-Clinical Higher selectivity and affinity than IL13 mutant used as targeting moiety of MB-101 (Mustang Bio)

For more information on partnering opportunities, please email: Dr. Shafique Fidai

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