Evolutionary cytokines, Revolutionary medicines

Medicenna is a clinical stage immunotherapy company that uses directed evolution to generate engineered interleukins called Superkines that can modulate, fine-tune or amplify the immune system in order to combat the most challenging diseases and inspire hope in patients with unmet needs.

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Platform

At the core of Medicenna’s therapies are engineered interleukins designed to improve upon the specificity, function, and safety profile of unmodified interleukins. These powerful and proprietary therapies are known as Superkines, and can modulate, fine-tune or amplify the immune system to fight cancer, autoimmune or neuroinflammatory diseases. Our approach allows us the flexibility to transform Superkines into multi-functional therapies that can be delivered directly to where they are needed the most. Medicenna’s initial focus is on developing interleukin-2 (IL-2), IL-4 and IL-13 super-agonists and antagonists.

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Events

Mar 22 – Mar 24, 2026

38th Annual ROTH Conference

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Press

Mar 18, 2026

Medicenna to Present Preclinical Data from its First-in-Class Tumor Anchored and Conditionally Activated Anti-PD-1-IL-2 Bifunctional Superkine at the AACR Annual Meeting 2026